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The main side effects of oxycodone withdrawal are the same as other opiates and opioids and are graded as being mild, moderate or severe.

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There are medications out there like clonidine that can help ease these symptoms during withdrawal and you should ALWAYS withdraw from pain killers with medical supervision. In the past five days I've experienced nite-time restlessness, excessive sweating, runny nose, and aggravation on a milder bases. And, will drinking a lot of water help flush this medication out of my system faster? For this reason, drinking water to speed up the metabolism of opioids is unlikely to work. Opioids like oxycodone, the main ingredient in Percocet, affect the opioid receptors in the nervous system and are some of the most powerful drugs known to man.But there's no way to stop taking Percocet totally without withdrawal symptoms, unfortunately. Persistent & severe shoulder pain required my being prescribed Percocet / Oxycodon while the diagnostic period took place for two months. After two months, the doctor gave me a Cortisone shot into my shoulder. (more info here: Use Disorder - Manual for Physicians.pdf) Oxycodone withdrawal symptoms tend to peak in the first 72 hours, and then taper off for 7-10 days afterwards. To clarify, you are most likely DEPENDENT on Percocet (oxycodone), and not addicted to Percocet. Withdrawing from oxycodone is an uncomfortable but necessary process to complete if you want to stay off narcotics for good.Be sure to drink water, especially if diarrhea is present, but don't count on water to help you eliminate oxycodone. Other people swear by mild exercise, hot baths, taking cranberry extract pills and drinking a lot of cranberry juice..I'm not sure about the scientific accuracy of these statements. I too am being prescribed percocet for migraines, painful cyst in my foot needing surgery, and a torn MCL w/bruised bone. If you'd like to try natural methods for detox, you might look into acupuncture or acupressure (see link below).Withdrawing from oxycodone is generally not life threatening.But some of the side effects can be very uncomfortable.When you no longer requires oxycodone hydrochloride tablets to treat pain, opioid therapy should be gradually discontinued over time to prevent opioid abstinence syndrome (oxycodone withdrawal).

In general, doses of oxycodone can be decreased by 25% to 50% per day with careful monitoring for signs and symptoms of withdrawal.

But most cases of oxycodone withdrawal will manifest AT LEAST the following side effects: Do not quit taking oxycodone suddenly or you could experience serious withdrawal symptoms If you decide to stop taking oxycodone suddenly, seek out medically supervised withdrawal (detoxification) with either opioid or nonopioid medications to help you manage symptoms.

If you decide to stop taking oxycodone cold turkey, be prepared to manage symptoms of withdrawal with the help of an outpatient or inpatient medical clinic, or from home.

With repeated exposure to opioids like oxycodone, however, the LC neurons adjust by increasing their level of activity.

Now, when opioids are no longer present to suppress the LC brain cells’ enhanced activity, the LC neurons release excessive amounts of noradrenaline, triggering the jitters, anxiety, muscle cramps, and diarrhea that are associated with opiate withdrawal.

I have a phobia of vomiting but want to stop taking percocet (still in pain but will deal with that once I'm off them)..